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catherine leonard

Catherine joined SCRUBS in the fall of 2021. Originally from the UK, Catherine has a B.Sc. from the University of Liverpool and a Master's degree from the University of Calgary. She is an experienced research laboratory technician, project manager and

Catherine photo_edited.jpg

Research Facilitator, MSc. 

Centre for Mobility and Joint Health 

Orthopaedic Research Portfolio 

scientific writer who has contributed to 40 journal publications and grant proposals that have raised $1.5 million in government funding for medical research.

When she in not in the lab, Catherine likes to ride her motorcycle, create art or see how far she can hit a golf ball into the trees.

PUBLICATIONS

  • Jablonski CL, Leonard C, Salo P, Krawetz RJ. CCL2 But Not CCR2 Is Required for Spontaneous Articular Cartilage Regeneration Post-Injury. J Orthop Res. 2019 Dec;37(12):2561-2574. doi: 10.1002/jor.24444. Epub 2019 Aug 30. PMID: 31424112.

  • Ren G, Whittaker JL, Leonard C, De Rantere D, Pang DSJ, Salo P, Fritzler M, Kapoor M, de Koning APJ, Jaremko JL, Emery CA, Krawetz RJ. CCL22 is a biomarker of cartilage injury and plays a functional role in chondrocyte apoptosis. Cytokine. 2019 Mar;115:32-44. doi: 10.1016/j.cyto.2018.11.030. Epub 2019 Jan 7. PMID: 30623804.

  • O'Brien K, Tailor P, Leonard C, DiFrancesco LM, Hart DA, Matyas JR, Frank CB, Krawetz RJ. Enumeration and localization of mesenchymal progenitor cells and macrophages in synovium from normal individuals and patients with pre-osteoarthritis or clinically diagnosed osteoarthritis.  Int J Mol Sci. 2017 Apr 5;18(4). pii: E774. doi: 10.3390/ijms18040774.

  • Iqbal SM, Leonard C, Regmi S, De Rantere D, Tailor P, Ren G, Ishida H, Hsu C, Abubacker S, Pang DS, T Salo P, Vogel HJ, Hart DA, Waterhouse CC, Jay GD, Schmidt TA, Krawetz RJ. Lubricin/Proteoglycan 4 binds to and regulates the activity of toll-like receptors in vitro.  Sci Rep. 2016 Jan 11;6:18910. doi: 10.1038/srep18910

  • Leonard CA, Lee WY, Tailor P, Salo PT, Kubes P, Krawetz RJ. Allogeneic bone marrow transplant from MRL/MpJ super-healer mice does not improve articular cartilage repair in the C57Bl/6 strain. PLoS One. 2015 Jun 29;10(6):e0131661. doi: 10.1371/journal.pone.0131661.

  • Mak J, Leonard C, Foniok T, Rushforth D, Dunn JF, Krawetz R. Evaluating endogenous repair of focal cartilage defects in C57BL/6 and MRL/MpJ mice using 9.4T magnetic resonance imaging: a pilot study. Magn Reson Imaging. 2015 Jun;33(5):690-4. doi: 10.1016/j.mri.2015.01.001. Epub 2015 Jan 15

  • Miller D, DeSutter C, Scott A, Koglin L, Hart DA, Salo P, Leonard C, Mammoto T, Bray RC. Vascular structure and function in the medial collateral ligament of anterior cruciate ligament transected rabbit knees. J Orthop Res. 2014 Sep;32(9):1104-10. doi: 10.1002/jor.22643. Epub 2014 Jun 7.

  • Miller DS, Salo P, Hart DA, Leonard C, Mammoto T, Bray RC: Comparison of vascular responses in the medial collateral ligament of ACL deficient rabbit knees and MCL transected rabbit knees: indirect evaluation of inflammation in healing ligaments and chronic ligament injury models. Submitted, 2011.

  • Mammoto T, Demcoe R, Miller D, Leonard C, Seerattan R, Bray RC, Salo P: Immediate ACL reconstruction prevents microvascular pathophysiology in the uninjured MCL that is not fully reversed by delayed ACL reconstruction. Journal of Orthopaedic Research, 29(9): 1390-396, 2011.

  • Miller, D, Salo P, Hart D, Leonard C, Bray RC: Neural stimulation does not mediate attenuated vascular response in ACL-deficient knees: potential role of inflammatory mediators. Journal of Orthopaedic Research, 28(1): 83-88, 2010.

  • Salo PT, Beye JA, Seerattan RA, Leonard CA, Ivie TJ, Bray RC: Plasticity of peptidergic innervation in healing rabbit medial collateral ligament. Can J. Surg 51(3): 167-172, 2008.

  • Beye JA, Hart DA, Bray RC, Seerattan RA, McDougall JJ, Leonard CA, Reno C, Salo PT: Injury induced changes in mRNA levels differ widely between anterior cruciate ligament and medial collateral ligament  American Journal of Sports Medicine, 36(7): 1337-1346, 2008.

  • Mammoto T, Seerattan RA, Paulson KD, Leonard CA, Bray RC, Salo PT: Nerve growth factor improves ligament healing. Journal of Orthopaedic Research, 26(7): 228-234, 2008.

  • Miller D, Forrester K, Leonard C, Hart DA, Salo P, Bray RC. Endothelial dysfunction and decreased vascular responsiveness in the anterior cruciate ligament deficient model of osteoarthritis. Journal of Applied Physiology 102: 1161 – 1169, 2007.

  • Beye JA, Hart DA, Bray RC, Seerattan RA, Leonard CA, Reno C, Salo PT: Denervation alters mRNA levels of repair-associated genes in a rabbit MCL injury model. Journal of Orthopaedic Research 24 (9):1842-1853, 2006.

  • Bray RC, Forrester KR, Reed J, Leonard C, and Tulip J:  Endoscopic laser speckle imaging of tissue blood flow: applications in the human knee. Journal of Orthopaedic Research, 24: 1650-1659, 2006.

  • Bray RC, Leonard C, Forrester K, Salo P: Animal models of ligament repair. In: Encyclopaedia of Biomaterials and Biomedical Engineering 1 (1), Dekker, 2005.

  • Miller D, Forrester K, Leonard C, Salo P, Bray RC. ACL deficiency and incipient osteoarthritis impairs the vasoconstrictive efficacy of neuropeptide Y in articular tissues: a laser speckle perfusion imaging study. Journal of Applied Physiology 98(1): 329-33, 2005.

  • Forrester KR, Tulip J, Leonard C, Stewart C, Bray RC. A laser speckle imaging technique for measuring tissue perfusion. IEEE Transactions on Biomedical Engineering 51(11): 1994-2005, 2004.

  • Bray RC, Forrester K, Leonard CA, McArthur R, Tulip J, Lindsay R: Laser Doppler imaging of burn scars: a comparison of wavelength and scanning methods. Burns 29(3) 199-206, 2003.

  • Bray RC, Leonard CA, Salo PT. Correlation of healing capacity with vascular response in the anterior cruciate and medial collateral ligaments of the rabbit. J Orthop Res. 2003 Nov; 21(6):1118-23.

  • Bray RC, Leonard CA, Salo PT. Vascular adaptation of intact joint stabilizing structures in the posterior cruciate ligament deficient rabbit knee. J Orthop Res. 2003 Sep; 21(5):787-91.

  • Bray RC, Leonard CA, Salo PT. Vascular physiology and long-term healing of partial ligament tears. J Orthop Res. 2002 Sep; 20(5):984-9.

  • Bray RC, Smith JA, Eng MK, Leonard CA, Sutherland CA, Salo PT. Vascular response of the meniscus to injury: effects of immobilization. J. Orthop Res. 2001 May; 19(3):384-90.

  • McDougall JJ, Yeung G, Leonard CA, Sutherland C, Bray RC. Adaptation of post-traumatic angiogenesis in the rabbit knee by apposition of torn ligament ends. J Orthop Res. 2000 Jul; 18(4):663-70.

  • McDougall JJ, Yeung G, Leonard CA, Bray RC. A role for calcitonin gene-related peptide in rabbit knee joint ligament healing. Can J Physiol Pharmacol. 2000 Jul; 78(7):535-40.

  • Tetzlaff W, Leonard C, Krekoski CA, Parhad IM, Bisby MA. Reductions in motoneuronal neurofilament synthesis by successive axotomies: a possible explanation for the conditioning lesion effect on axon regeneration. Exp Neurol. 1996 May; 139(1):95-106.

  • Heyes MP, Papagapiou M, Leonard C, Markey SP, Auer RN. Effects of profound insulin-induced hypoglycemia on quinolinic acid in hippocampus and plasma. Adv Exp Med Biol. 1991; 294:679-82.

  • Heyes MP, Papagapiou M, Leonard C, Markey SP, Auer RN. Brain and plasma quinolinic acid in profound insulin-induced hypoglycemia. J Neurochem. 1990 Mar; 54(3):1027-33.

  • Tetzlaff W, Gilad VH, Leonard C, Bisby MA, Gilad GM. Retrograde changes in transglutaminase activity after peripheral nerve injuries. Brain Res. 1988 Mar 29; 445(1):142-6.

Contact

cleonard@ucalgary.ca

(403) 852-2035

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