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Dr. James Mackenzie

Orthopaedic Surgeon, BSc., MD, FRCS(C)

Arthroplasty Hip, Knee & Trauma Surgeon 

Clinical Lecturer, University of Calgary

Dr. MacKenzie is an Orthopedic Surgeon with a focus on total joint arthroplasty at South Health Campus.


He is active as a teacher in the Orthopaedic Residency Program and he is also a member of the Clinical Steering Committee for the Alberta Hip and Knee Provincial Care plan. He is also an involved researcher at South Health Campus. 


Dr. James MacKenzie attended the University of Alberta in Edmonton, Canada for his Bachelor of Science Undergraduate degree and went on to complete his Medical Degree at the University of Alberta as well. He then took on a transitional internship for a year in Akron Ohio, USA and completed residency in 1990 at the University of Calgary, Canada. Dr. MacKenzie completed two Fellowships, one at the Royal College of Surgeons (Orthopedics) Canada and an additional Fellowship in Total Joint Replacement at the University of Iowa, USA.

research interests 

Dr. MacKenzie's main research interests have been on research focused on total hip arthroplasty.

Dr. MacKenzie is the principal investigator of the Alberta Hip Improvement Project, a study looking to determine the effectiveness and safety of the use of metal-on-metal hip resurfacing when compared to conventional total hip replacement. He is also part of the research team of a nation-wide observational study following proximal humerus fractures in the elder population, called DECIPHER. 

More recently, Dr. MacKenzie has become involved as a co-investigator in the OR3O study at South Health Campus, a prospective, multi-center trial trying to evaluate the safety and effectiveness of the OR3O™ Dual Mobility System in Primary and Revision Total Hip Arthroplasty (THA).


  • MacKenzie, J.R., Callaghan, J.J., Brown, T.D., Pedersen, D.R.: Areas of contact and extent of gaps with implantation of over-sized acetabular components in total hip arthroplasty. Clinical Orthopedics, Jan 1994.

  • MacKenzie, J.R., Kelley, S.S., Johnston, R.C., Total hip replacement for coxarthrosis secondary to congenital dysplasia and dislocation of the hip. J. Bone and Joint Surg., 78A: 55-61, Jan 1996.

  • Sullivan, P.M., MacKenzie, J.R., Callaghan, J.J., Johnston, R.C., Total hip arthroplasty with cement in patients who are less than fifty years old. A sixteen to twenty-two year follow-up study. J. Bone and Joint Surg., 76A: 863-869, June 1994. 

  • MacKenzie JR, O’Connor GJ, Marshall DA, Faris PD, Dort LC, Khong H, Parker RD, Werle JR, Beaupre LA, Frank CB (2012). Functional outcomes for 2 years comparing hip resurfacing and total hip arthroplasty. J Arthroplasty. May, 27(5):750-7.e2.

  • Shandiz MA; MacKenzie JR; Hunt S; Anglin C (2015) Accuracy of an adjustable patient-specific guide for acetabular alignment in hip replacement surgery (Optihip). Proc Inst Mech Eng H 2014 Sep;228(9):876- 89  



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